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TB-500

TB-500

CAS #: 77591-33-4

Certificate of Analysis PP-9645060 10mg Purity Report Endotoxin Report

Research Use Only

Peptide Portal supplies research peptides exclusively to qualified researchers and laboratories for in vitro and laboratory use. Products are not for human or veterinary use, not for use in diagnostic procedures, and have not been evaluated by the U.S. Food and Drug Administration.

TB-500 Overview

TB-500 is a synthetic peptide fragment derived from thymosin beta-4, a naturally occurring protein studied for its role in molecular signaling and pathway dynamics. Research has focused on its potential influence on matrix remodeling, angiogenesis, and molecular migration in preclinical and laboratory models. TB-500 is of particular interest in investigations involving connective tissue, structural dynamics, and extracellular matrix pathways.

Goldstein A.L. et al. (2005).

History

Thymosin Beta-4, the parent protein of TB-500, was first isolated in the 1960s by Allan L. Goldstein and colleagues during research into thymus-derived peptides. TB-500 was later synthesized as a research fragment to enable focused study on Tβ4's signaling functions. Since its development, it has been investigated across models of angiogenesis, structural dynamics, and molecular migration, with growing interest in its systemic regulatory potential.

Goldstein A.L., Hannappel E. et al. (2012).

TB-500 Structure

TB-500 structure diagram
CAS #:
77591-33-4
Molecular Formula:
C₂₁₂H₃₅₀N₅₆O₇₈S
Molecular Weight:
4963.5 g/mol
PubChem ID:
16132321

Our Process

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STEP 1

Sterile Lyophilization

Compounds are produced under documented quality procedures, then freeze-dried and nitrogen-sealed in sterile vials.

STEP 2

Independent Verification

ISO 17025 accredited third-party labs verify every lot — purity by HPLC, identity by mass spectrometry.

STEP 3

Rapid Dispatch

Orders leave our U.S. fulfillment center the same day, with tracking and discreet packaging on every order.

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Our team works around the clock, 24/7.

Frequently Asked Questions

Everything you need to know about our products and processes.

Each vial contains the labelled quantity of lyophilized peptide. The stated milligram figure refers to the peptide content, not the total mass of the lyophilized cake.

Reconstitution requires bacteriostatic water and appropriate laboratory equipment, which are not included.

Products ship as research materials without directions for use. Handling should follow your own laboratory protocols.

Store lyophilized material at 2-8°C and away from light. Once reconstituted, follow your laboratory's stability guidance.