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SS-31

SS-31

CAS #: 736992-21-5

Certificate of Analysis PP-1264076 10mg Purity Report Endotoxin Report

Research Use Only

Peptide Portal supplies research peptides exclusively to qualified researchers and laboratories for in vitro and laboratory use. Products are not for human or veterinary use, not for use in diagnostic procedures, and have not been evaluated by the U.S. Food and Drug Administration.

SS-31 Overview

SS-31 is a synthetic tetrapeptide composed of four amino acids. It was originally developed as part of the Szeto-Schiller peptide series, a class of aromatic-cationic compounds designed to concentrate within the inner mitochondrial membrane. Since its characterization in the early 2000s, SS-31 has been studied extensively in controlled experimental settings for its potential influence on cardiolipin stabilization, reactive oxygen species, and mitochondrial bioenergetics.

Zhao K. et al. (2004).

History

The peptide was first developed by Hazel Szeto and Peter Schiller at Weill Cornell Medical College while investigating antioxidants that could reach the primary site of free-radical generation. Early experiments focused on its ability to concentrate at the inner mitochondrial membrane and preserve mitochondrial integrity under oxidative stress. Over time, studies broadened into cardiac, neuronal, renal, and systemic systems, where SS-31 (later developed as elamipretide) consistently demonstrated properties of interest in the context of mitochondrial function and biological resilience.

Birk A.V. et al. (2013).

SS-31 Structure

SS-31 structure diagram
CAS #:
736992-21-5
Molecular Formula:
C₃₂H₄₉N₉O₅
Molecular Weight:
639.80 g/mol
PubChem ID:
11764719

Our Process

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STEP 1

Sterile Lyophilization

Compounds are produced under documented quality procedures, then freeze-dried and nitrogen-sealed in sterile vials.

STEP 2

Independent Verification

ISO 17025 accredited third-party labs verify every lot — purity by HPLC, identity by mass spectrometry.

STEP 3

Rapid Dispatch

Orders leave our U.S. fulfillment center the same day, with tracking and discreet packaging on every order.

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Our team works around the clock, 24/7.

Frequently Asked Questions

Everything you need to know about our products and processes.

Each vial contains the labelled quantity of lyophilized peptide. The stated milligram figure refers to the peptide content, not the total mass of the lyophilized cake.

Reconstitution requires bacteriostatic water and appropriate laboratory equipment, which are not included.

Products ship as research materials without directions for use. Handling should follow your own laboratory protocols.

Store lyophilized material at 2-8°C and away from light. Once reconstituted, follow your laboratory's stability guidance.