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Thymosin Alpha 1

Thymosin Alpha 1

CAS #: 62304-98-7

Certificate of Analysis PP-9585603 10mg Purity Report Endotoxin Report

Research Use Only

Peptide Portal supplies research peptides exclusively to qualified researchers and laboratories for in vitro and laboratory use. Products are not for human or veterinary use, not for use in diagnostic procedures, and have not been evaluated by the U.S. Food and Drug Administration.

Thymosin Alpha 1 Overview

Thymosin Alpha 1 functions as a potent immunomodulator that influences signaling dynamics, cytokine expression, and immune pathway homeostasis. As a naturally occurring 28-amino acid peptide originally isolated from thymic tissue, Tα1 has been studied for its role in thymocyte signaling, immune pathway differentiation, and innate and adaptive response regulation. Through toll-like receptor (TLR) pathway activation and signaling modulation, Tα1 has been investigated in research models examining thymocyte dynamics, dendritic signaling, natural killer pathway activity, and multi-system immune responses in laboratory settings. Liu et al. (2023).

Romani et al. (2007).

History

Thymosin Alpha 1 was first isolated and characterized from bovine thymus gland in the 1970s by Allan Goldstein and colleagues at George Washington University. This peptide was identified as the primary active component of thymosin fraction 5, a crude thymic extract with immunological activity. Subsequent research established its role in thymocyte differentiation and led to development as thymalfasin for continued experimental investigation.

Goldstein et al. (2010).

Thymosin Alpha 1 Structure

Thymosin Alpha 1 structure diagram
CAS #:
62304-98-7
Molecular Formula:
C₁₂₉H₂₁₅N₃₃O₅₅
Molecular Weight:
3108.28 g/mol
PubChem ID:
16132341

Our Process

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STEP 1

Sterile Lyophilization

Compounds are produced under documented quality procedures, then freeze-dried and nitrogen-sealed in sterile vials.

STEP 2

Independent Verification

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STEP 3

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Frequently Asked Questions

Everything you need to know about our products and processes.

Each vial contains the labelled quantity of lyophilized peptide. The stated milligram figure refers to the peptide content, not the total mass of the lyophilized cake.

Reconstitution requires bacteriostatic water and appropriate laboratory equipment, which are not included.

Products ship as research materials without directions for use. Handling should follow your own laboratory protocols.

Store lyophilized material at 2-8°C and away from light. Once reconstituted, follow your laboratory's stability guidance.