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L-Glutathione

L-Glutathione

CAS #: 70-18-8

Certificate of Analysis PP-6780313 1000mg Purity Report Endotoxin Report

Research Use Only

Peptide Portal supplies research peptides exclusively to qualified researchers and laboratories for in vitro and laboratory use. Products are not for human or veterinary use, not for use in diagnostic procedures, and have not been evaluated by the U.S. Food and Drug Administration.

L-Glutathione Overview

L-Glutathione is a ubiquitous tripeptide present in virtually all living organisms, serving as a primary intracellular antioxidant and redox regulator. In its reduced form (GSH), it participates in neutralizing reactive oxygen species (ROS), maintaining redox homeostasis, and supporting the integrity of proteins, lipids, and DNA against oxidative stress. Through its sulfhydryl group on the cysteine residue, glutathione acts as a substrate for peroxidase enzymes that reduce hydrogen peroxide and lipid peroxides. Research models examine its role in phase II conjugation pathways, molecular proliferation and signaling, mitochondrial function, and protein folding regulation in laboratory settings. Forman et al. (2009).

Lu (2013).

History

Glutathione was first discovered in 1888 by J. de Rey-Pailhade as a sulfur-containing compound in yeast and animal tissues, initially termed "philothion." The complete chemical structure as a γ-glutamylcysteinylglycine tripeptide was elucidated in 1935 by Frederick Gowland Hopkins, who received the Nobel Prize for his contributions to vitamin discovery. Since then, glutathione has been recognized as a fundamental molecule in cellular biochemistry and redox biology.

Meister & Anderson (1983).

L-Glutathione Structure

L-Glutathione structure diagram
CAS #:
70-18-8
Molecular Formula:
C₁₀H₁₇N₃O₆S
Molecular Weight:
307.32 g/mol
PubChem ID:
124886

Our Process

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STEP 1

Sterile Lyophilization

Compounds are produced under documented quality procedures, then freeze-dried and nitrogen-sealed in sterile vials.

STEP 2

Independent Verification

ISO 17025 accredited third-party labs verify every lot — purity by HPLC, identity by mass spectrometry.

STEP 3

Rapid Dispatch

Orders leave our U.S. fulfillment center the same day, with tracking and discreet packaging on every order.

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Our team works around the clock, 24/7.

Frequently Asked Questions

Everything you need to know about our products and processes.

Each vial contains the labelled quantity of lyophilized peptide. The stated milligram figure refers to the peptide content, not the total mass of the lyophilized cake.

Reconstitution requires bacteriostatic water and appropriate laboratory equipment, which are not included.

Products ship as research materials without directions for use. Handling should follow your own laboratory protocols.

Store lyophilized material at 2-8°C and away from light. Once reconstituted, follow your laboratory's stability guidance.