STEP 1
Sterile Lyophilization
Compounds are produced under documented quality procedures, then freeze-dried and nitrogen-sealed in sterile vials.
Kisspeptin
CAS #: 374675-21-5
Research Use Only
Peptide Portal supplies research peptides exclusively to qualified researchers and laboratories for in vitro and laboratory use. Products are not for human or veterinary use, not for use in diagnostic procedures, and have not been evaluated by the U.S. Food and Drug Administration.
Kisspeptin Overview
Kisspeptin represents a central signaling molecule in the hypothalamic-pituitary-gonadal (HPG) axis, acting as a key modulator of neuroendocrine signaling. As a family of peptides ranging from kisspeptin-10 to kisspeptin-54, these molecules bind to their target receptor (KISS1R) and play essential roles in neuroendocrine research. Through KISS1R activation on target neurons, kisspeptin influences pulsatile signaling dynamics, developmental pathway initiation, and endocrine regulation. Research models examine its role in neuroendocrine signaling cascades, feedback loop dynamics, and developmental biology. Jayasena et al. (2014).
Trevisan et al. (2018).
History
Kisspeptin was initially identified in 1996 as a metastasis suppressor gene product in melanoma research, leading to its original name 'metastin.' The critical neuroendocrine role was discovered in 2003 when loss-of-function mutations in KISS1 and KISS1R were found to be associated with HPG axis signaling disruption in experimental and observational studies. This breakthrough established kisspeptin as a key modulator of endocrine signaling and sparked extensive neuroendocrine research.
Mills & Dhillo (2022).
Kisspeptin Structure
- CAS #:
- 374675-21-5
- Molecular Formula:
- C₆₃H₈₃N₁₇O₁₄
- Molecular Weight:
- 1302.45 g/mol
- PubChem ID:
- 25240297
STEP 2
Independent Verification
ISO 17025 accredited third-party labs verify every lot — purity by HPLC, identity by mass spectrometry.
STEP 3
Rapid Dispatch
Orders leave our U.S. fulfillment center the same day, with tracking and discreet packaging on every order.
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Each vial contains the labelled quantity of lyophilized peptide. The stated milligram figure refers to the peptide content, not the total mass of the lyophilized cake.
Reconstitution requires bacteriostatic water and appropriate laboratory equipment, which are not included.
Products ship as research materials without directions for use. Handling should follow your own laboratory protocols.
Store lyophilized material at 2-8°C and away from light. Once reconstituted, follow your laboratory's stability guidance.
